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Background: Esophageal Cancer (EC) is the eighth most common cancer in terms of incidence. Despite various studies, there is no general estimate of EC incidence in Iran. Therefore, the present study is conducted to evaluate the incidence rates of EC in Iran.

Method: A systematic search was conducted on all published studies of EC incidence using Medline/PubMed, Scopus, Web of sciences, Google scholar, and four Iranian databases (Scientific Information Database, MagIran, IranMedex, and IranDoc) until November 2017. This systematic review was done according to the preferred reporting items for systematic reviews and meta-analyses (PRISMA).

Result: The database, grey literature searches, and hand searching yielded 346 potentially relevant studies. A total of 22 studies were included. The results of the random effect model were demonstrated the age-standardized rate (ASR) of EC was 25.05, 95% CI (20.84 to 29.26) among males and 22.93 95 % CI (18.97-26.88) among females.

Conclusion: In comparison to other geographical locations, the incidence of EC is higher in Iran. However, organized system for collecting data of cancer is required to specify the incidence and trend of EC in Iran.

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Article Details

Issue: Vol 5 No 7 (2018)
Page No.: 2493-2503
Published: Jul 27, 2018
Section: Reviews

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Copyright: The Authors. This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 4.0., which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 How to Cite
Salehiniya, H., Hassanipour, S., Mansour-Ghanaei, F., Mohseni, S., Joukar, F., Abdzadeh, E., Fathalipour, M., & Arab-Zozani, M. (2018). The Incidence of Esophageal Cancer in Iran: A Systematic Review and Meta-analysis. Biomedical Research and Therapy, 5(7), 2493-2503.

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