TY - JOUR AU - Hamidreza Sadeghi Gandomani AU - Abed Asgari Tarazoj AU - Hamid Salehiniya PY - 2017/09/20 Y2 - 2024/03/29 TI - Cigarette: The Silent Killer in the World JF - Biomedical Research and Therapy JA - BMRAT VL - 4 IS - 9 SE - Letter to Editor DO - 10.15419/bmrat.v4i9.369 UR - http://bmrat.org/index.php/BMRAT/article/view/369 AB - One of the main challenges of the 21st century is tobacco consumption, and in particular cigarette smoking (Control and Prevention, 2012). Cigarette smoking is a leading cause of death worldwide (Control and Prevention, 2011).About 1 billion people around the world (800 million men and 200 million women) are addicted to cigarette (WHO, 2015). The prevalence of smoking varies across different parts of the world; this variation is due to economic development and income levels. More than 80% of adult male smokers and half of adult female smokers live in low or middle-income countries  (Ng et al., 2014).Tobacco use kills more than 7 million people every year worldwide, and nearly 80% of these deaths occur in low-income countries (WHO, 2017). It is estimated that this figure will increase in 2030 (WHO, 2011). Tobacco use caused 100 million deaths in the 20th worldwide, if this trend continues, this figure will reach 1 billion by the end of the 21st century (Thun et al., 2013). ER -