TY - JOUR AU - Galyna Fadeenko AU - Alexey Gridnyev AU - Nataliya Emelyanova AU - Nataliya Chereliuk PY - 2021/11/29 Y2 - 2024/03/28 TI - A case of a long course of Osler–Weber–Rendu disease in a 65-year-old patient JF - Biomedical Research and Therapy JA - BMRAT VL - 8 IS - 11 SE - Case report DO - 10.15419/bmrat.v8i11.704 UR - http://bmrat.org/index.php/BMRAT/article/view/704 AB - The incidence of Osler–Weber–Rendu disease is low, ranging from 1 detected case per 50,000 to 1 per 100,000 population. The disease is hereditary, with autosomal dominant transmission, caused by pathogenic mutations in genes involved in angiogenesis. The disease has a pronounced clinical picture of multiple telangiectasias of the skin and mucous membranes and manifests as spontaneous bleeding. This scientific article presents a clinical analysis of a 65-year-old patient with a diagnosis of Osler–Weber–Rendu disease. Early identification of the manifestations of this disease and careful observation of the patient give a favorable prognosis of the course and prevent the development of severe complications. ER -